Did you know?

  • 1 in 3 women and 1 in 5 men at risk of fracture
  • Fractures most commonly occur in the hip, spine and wrist
  • Current trends predict the number of fractures could triple by 2050



Osteoporosis is a bone disease characterised by break down of bone structure and decrease in bone mass. This results in increased fragility and consequently, the risk of fractures in bones.

Globally, it is estimated that over 200 million people suffer from osteoporosis.

Patients who experience fractures as a result of osteoporosis are likely to experience a reduced quality of life and potentially life span. Up to 20% mortality has been recorded after hip fracture and of those who survive, 50% cannot walk within 1 year.

The cause of osteoporosis is generally unknown, with only 3% accounted for by known genetic variation. However, heritability of 60–90% suggests genetic variation might play a larger role than currently realised.

Current treatments only reduce fracture risk by 50% – highlighting an urgent need for improved treatments.

Further information about osteoporosis can be found at:

X-ray image of osteoporotic vertebrae showing thinning of the bone